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HPLC/UHPLC Troubleshooting

12 October 2015, Hoddesdon, United Kingdom


Introduction
HPLC and UHPLC Troubleshooting:
A Performance Qualification Approach (1 day)

A comprehensive course in the isolation, correction and prevention of problems in liquid chromatography

Who should take this course?

This course is designed for anyone who works with HPLC or UHPLC. No previous experience with HPLC or UHPLC systems is assumed; however, much of the course will also appeal to the more experienced chromatographer.

What does it cover?

"HPLC & UHPLC Troubleshooting" is an intensive one day course that teaches you how to solve the common problems that can occur with your LC methods. You will learn how to qualify the performance of your HPLC/UHPLC instrument using specific tests that can also be used for isolating existing problems. You'll also learn how to prevent many of these problems from occurring in the first place. This course covers:

• Operating principles of each module in an HPLC/UHPLC system
• Review of HPLC theory as it applies to troubleshooting and instrument maintenance
• Why performance qualification (PQ) is so important
• Proven techniques for systematic problem solving and instrument maintenance
• The most effective, time saving and money saving approaches to preventing common hardware problems and method failures

What will I get from this course?

What you learn will demystify your instrument. You'll find that all of the perplexing and frustrating problems you experience have straightforward and logical solutions. More importantly, you'll learn that most of these problems are preventable. The techniques you learn from this course will make you more effective at work and save you big headaches! Delegates tell us that this "extremely practical course" is a must for everyone who uses HPLC or UHPLC.

Course Outline

Principles of HPLC & UHPLC troubleshooting
Performance qualification, part 1: pump & detector
PQ, part 2: on-line mixing
PQ, part 3: chromatographic checks
The separation: physical problems with columns
The separation: chemical problems with columns
Problems with quantification
Speakers
  • John Dolan LC Resources, CA, United States

Venue
Merck, Sharp & Dohme Ltd

TBC, Merck, Sharp & Dohme Ltd, Hertford Road, Hoddesdon, EN11 9BU, United Kingdom

Organised by
Hichrom Ltd
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